Selected Videos Online

Alzheimer's Disease

Alzheimer's Disease (Alzheimer's or Alzheimer) is a type of Dementia and it is the most common type of dementia. It is not a normal or regular part of aging and currently there is no known cure for Alzheimer's.

It is a degenerative brain disease that negatively affects an individual's memory, thinking, language, judgment and behavior. In addition to losing all memory of people, places and events a person with Alzheimer's will eventually lose the ability to walk and talk as well as the ability to bathe and feed himself or herself.

Causes of Alzheimer's Disease

The causes of Alzheimer's are not fully understood but it appears that abnormal amyloid plaques and neurofibrillary tangles play a role in the death of a brain's nerve cells (neurons) which have negative effects on an individual's brain functions. The plaques build up between the nerve cells and the tangles within the nerve cells.

In recent years billions of dollars have been spent on research to try and determine the extent to which genetics and other factors cause Alzheimer's. In most discussions medical professionals distinguish between early-onset and late-onset Alzheimer's Disease.

Early-Onset and Late-Onset Alzheimer's

Early-onset Alzheimer's Disease occurs before the age of 60 or 65 and represents less than 5 percent of all people who have Alzheimer's. Some cases of early-onset Alzheimer's have no known cause, but most cases are inherited and are known as familial Alzheimer's Disease. Familial Alzheimer's Disease is caused by any one of a number of different mutations in 3 genes - the amyloid precursor protein (APP), presenilin 1 and presenilin 2 genes.

Most cases (about 95%) of Alzheimer's Disease are considered late-onset and usually develop after the age of 60 or 65. The causes of late-onset Alzheimer's Disease are not yet fully understood, but most research indicates that they include a combination of genetic, environmental, and lifestyle factors.

Diagnosing Alzheimer's Disease

A change in an individual's behavior might appear to some as Alzheimer's Disease but it may be another form of dementia which can be reversed. Only a competent medical professional should attempt to diagnose the causes of an individual's change in behavior.

Medications for Alzheimer's Disease

There are two types of medications or drugs that are currently prescribed to most people with Alzheimer's Disease but both treat only the symptoms of the disease and are not cures. Cholinesterase inhibitors affect the level of a chemical called acetylcholine in the brain and Memantine affects the level of of glutamate, a chemical messenger in the brain.

Research on new medications and the testing of new drugs is ongoing and there are currently over 100 trials for treatments and medications for Alzheimer's and dementia.

Selected Videos

We select videos that can be watched for free and online. These videos provide reports and discussions about the most recent information learned about Alzheimer's Disease - the causes, brain aging, genetics, early detection, social behavior, diagnosis and treatment, new drugs and medications, prevention and more.

Some videos are relatively short (under 20 minutes) and cover a very specific subject - like how Alzheimer's spreads from brain cell to brain cell. Other Selected Videos are longer (50 minutes or more) and cover multiple aspects of Alzheimer's - like a basic explanation of how the brain works, an explanation of brain aging and Alzheimer's, followed by a discussion of research results relating to the causes and potential medications for Alzheimer's Disease.

Videos About Alzheimer's Disease

"Lisa Genova: What you can do to prevent Alzheimer's"

Lisa Genova
Time: 14 minutes
Producer: TED Talks
Lisa Genova, PhD, a neuroscientist and author of Still Alice, explains why she believes that an Alzheimer's cure will likely be the prevention or slowing down of the onset of Alzheimer's.

"Longevity: Tales from the Oldest Old Presented by Claudia H. Kawas, M.D."

The 90+ Study
Time: 60 minutes
Producer: UCI Media Services
Claudia Kawas, MD, a Co-Principal Investigator at the 90+ Study, reports on some recent findings of the study.

"Mayo Clinic Study of Thousands of Brains Reveals Tau as Driver of Alzheimer's Disease"

Melissa Murray
Time: 1 minutes
Producer: Mayo Clinic
Melissa Murray, PhD, a neuroscientist at Mayo Clinic in Jacksonville, Florida, explains how researchers examined 3,600 postmortem brains.

"Alzheimer's Disease Clinical Trials: Dr. Laurie Ryan"

Laurie Ryan
Time: 5 minutes
Producer: National Institute on Aging
Dr. Laurie Ryan of the National Institute on Aging/NIH describes how clinical trials are advancing Alzheimer's research.

"Approaches to Aging and Alzheimer's: What are We Learning from Clinical Trials? - Rachelle Doody"

Rachel Doody
Time: 33 minutes
Producer: SENS Foundation
Rachelle Doody, MD, PhD, discusses the risk factors for sporadic or late-onset Alzheimer's Disease as well as the plaques and tangles and the cognitive loss necessary for an Alzheimer's diagnosis

"Down Syndrome and Alzheimer's Disease
- On Our Mind"

Down Syndrome and Alzheimer's Disease
Time: 14 minutes
Producer: UCTV
William Mobley, MD, PhD and Michael Rafii, MD, PhD discuss what can be learned from people with Down Syndrome about Alzheimer's Disease.

"What You Need to Know: Alzheimer's Disease"

Alzheimer's Disease and Memory
Time: 3 minutes
Producer: Columbia University
Dr. Richard Mayeux of Columbia University explains the basics of Alzheimer's disease and ways to reduce the risk of Alzheimer's.

"Study: Self-Administered Test Helps Spot Early Alzheimer's"

Test for Alzheimer's
Time: 2 minutes
Producer: OSU Wexner Medical Center
This is a report on a self-administered test that can help predict Alzheimer's Disease in its earliest stages.

"Alzheimer's researchers seek better prevention with early detection"

PBS Preventing Alzheimer's
Time: 8 minutes
Producer: PBS
PBS reports on new efforts to begin treatment for Alzheimer's Disease before symptoms appear.

"Brain Mapping: Implications For Alzheimer's Research"

Brain Mapping Alzheimer's
Time: 90 minutes
Producer: Alzheimer's Association, New York City Chapter
A discussion of Brain Mapping and Alzheimer's Disease - Dr. Max Gomez, Peter Davies, Mony J. de Leo and Scott Small.